FSR feels strongly that the causes of this disease, and
ultimately a cure, will be uncovered through rigorous
and extensive scientific research. FSR research awards
focus on collaborations which will advance an improved
understanding of sarcoidosis and will address the causes
of the disease, the suffering of patients and the
potential for a cure for sarcoidosis. Learn more about FSR's Research Grant Application Process or Donate to
support important new research.
Meet Elliott Crouser, MD
Recipient of 2008 FSR-ATS
Partnership Grant for Sarcoidosis & 2008 K.I.S.S. Investigator Award
Dr. Crouser is Director of the Sarcoidosis Specialty Clinic at
the Ohio State University Medical Center.
He has extensive experience in both basic and translational research
and received a jointly sponsored FSR-ATS $100,000 award for a
novel approach to treating this disease. He was also
recognized for his clinical work with the 2008 K.I.S.S. Investigator
Award.
Summary: "Modulation of Pulmonary Sarcoidosis
by Nicotinic Acetylcholine Receptors"
Until recently, there was no good explanation for the fact that
smoking cigarettes reduces the risk of sarcoidosis. Research studies
have shown that the nicotine, a common component of cigarette smoke,
strongly suppresses the immune system and reduces the type of
inflammation that is characteristic of sarcoidosis in the lungs. Dr.
Crouser proposes that nicotine treatment, administered in the form
of a skin patch, will reduce the severity of lung disease in
patients with sarcoidosis. If his hypothesis is proven to be correct
in this relatively first study, he will perform additional studies
in a larger group of patients and will consider the features of
sarcoidosis patients that predict a favorable response to nicotine
and other nicotine-like drugs. If nicotine is ultimately found
to be an effective treatment for sarcoidosis, it may replace some of
the existing treatments which are frequently ineffective or have
unpleasant side-effects.
Click Here to learn how to participate in this trial which will
run through 2010.
K.I.S.S. Investigator Award
Dr. Crouser is joined by FSR President Andrea Wilson,
Co-honoree Karen Duffy and FSR Executive Director Debbie Durrer at
the 2008 KISS Chicago event. Emcees Peggy Kusinski and Rob
Elgas highlighted Dr. Crouser's achievements in
basic and clinical research and how they are likely to have a
significant impact on patient care in the years to come. |